In response, the state said it will deny new certificates of Assured Water Supply, which enable home construction.Īrizona has imposed such restrictions on other areas, and not all of greater Phoenix requires a certificate, but experts said the measure was certain to slow home-building in an area representing over half the state’s population that has become a magnet for people in the US searching for affordable housing. The state’s recently concluded analysis projected a water shortfall of 4.86m acre-feet (6bn cubic meters) in the Phoenix area over the next 100 years. "The suspect ran after Lauren and then sprinted away before returning to the location where Lauren's body was found and climbing over the barbed wire," read Zion Teasley's probable cause statement.Arizona, one of the driest states in the US, gets about a third of its water from the Colorado River, with approximately another 40% coming from groundwater sources. Security cameras in the area recorded Heike and the suspect walking along the same path within a short time frame around the time of the murder. Her belongings were found scattered along the trail. ![]() Investigators suspect that the woman had been chased down over a barbed wire fence at some point during the ordeal based on the condition of her clothes. There were also defensive wounds on her hands and forearms. FOX 10's Justin Lum reports.Īccording to newly released court documents, Heike was found with 15 stab wounds. The suspect, identified as Zion Teasley, was arrested about 1.5 miles away from where the murder happened, and police have released new details surrounding the investigation, as well as Teasley's arrest on May 4. DNA, video evidence led to arrestĭetails in Lauren Heike murder probe releasedĭays after a woman was killed along a hiking trail in North Phoenix, police have arrested the person they believe is responsible for the murder. ![]() We asked if Teasley's mother has assisted police in any way, but officials say she has refused to speak with authortities. We have also learned that Teasley's mother works for the Maricopa County Adult Probation Department. He is the same man who was seen in blurry surveillance footage running from the trail around the time Lauren Heike was attacked, officials said. ![]() He told investigators it was because his aunt died, but that has yet to be confirmed. Prosecutors say the 22-year-old had a plane ticket to Detroit. However, since Teasley is on probation for a past conviction, he could remain behind bars. That apartment complex is approximately 1.5 miles away from the crime scene.ĭNA, video and cell phone evidence all linked him to the crime, prosecutors allege.Ī judge set the suspect's bond at $1 million. As a result of a plea deal, Teasley served time from July 2021 until November 2022.Īccording to Teasley's pre-trial services court report, he was only given a 2 for his new criminal activity score.Īs for the case involving Heike's murder, investigators said Teasley was arrested at the apartment complex where he lived. He was arrested shortly after, and eventually pled guilty. On one occasion, court documents state Teasley pointed a gun at a clerk. They stemmed from a string of seven thefts that occurred repeatedly at two convenience stores between the May 15 to July 4, 2020.Īccording to the documents, Teasley would often inform clerks that he was committing a robbery, jumping behind counters, and direct them to put hundreds of dollars on Google Play cards. ![]() FOX 10's Lauren Clark reports.Ĭourt documents are giving glimpse into Teasley's criminal past, which include previous charges for robbery, kidnapping and aggravated assaults with a deadly weapon. Lauren Heike murder: New details on suspect's criminal pastĪs the investigation into a man who allegedly killed a woman along a North Phoenix hiking trail continues, court documents are revealing details on Zion Teasley's past encounters with the law.
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![]() Received: SeptemAccepted: MaPublished: April 21, 2023Ĭopyright: © 2023 Wang et al. Haugh, North Carolina State University, UNITED STATES To make temporal mitochondrial network tracking widely accessible, MitoTNT comes with an easy-to-use tracking module, an interactive 4D visualization capability, and powerful post-tracking analyses.Ĭitation: Wang Z, Natekar P, Tea C, Tamir S, Hakozaki H, Schöneberg J (2023) MitoTNT: Mitochondrial Temporal Network Tracking for 4D live-cell fluorescence microscopy data. Using MitoTNT, we uncovered distinct network movement patterns, fission and fusion preferences, and network-level responses to drugs. MitoTNT achieves >90% tracking accuracy in synthetic ground-truth datasets and agrees well with previously published motility values from experimental data. MitoTNT uses the distance and topology information in the mitochondrial network to track the mitochondria over time. Here, we present the software MitoTNT ( Mitochondrial Temporal Network Tracking) to solve this data analysis problem. The current challenge has been the lack of analysis tools to extract quantitative information from the enormous LLSM datasets. These four-dimensional networks (space and time) could only recently be captured through advanced imaging methods such as lattice light-sheet microscopy (LLSM). Contrary to the bean-shaped textbook depiction, mitochondria form large interconnected and dynamic network structures in cells. Mitochondria dysfunctions underlie many human diseases, including cancer, diabetes, cardiovascular and neurodegenerative diseases. Mitochondria are the powerhouses of the cell and assume critical roles in cell fate, cell signaling, and cellular health. MitoTNT’s easy-to-use tracking module, interactive 4D visualization capability, and powerful post-tracking analyses aim at making temporal network tracking accessible to the wider mitochondria research community. We showed that pharmacological perturbations increase network reachability but decrease network resilience through a combination of altered mitochondrial fission/fusion dynamics and motility. Finally, we developed graph-based transport simulations that model how material would distribute on experimentally measured mitochondrial temporal networks. ![]() We found that mitochondrial skeleton nodes near the fission/fusion sites move nearly twice as fast as random skeleton nodes and that microtubules play a role in mediating selective fission/fusion. Second, we identified fission and fusion events with high spatiotemporal resolution. We revealed that the skeleton node motion is correlated along branch nodes and is uncorrelated in time. First, we characterized sub-fragment motility and analyzed network branch motion patterns. We used MitoTNT to quantify 4D mitochondrial networks from human induced pluripotent stem cells. We found that our tracking is >90% accurate for ground-truth simulations and agrees well with published motility results for experimental data. To validate the accuracy of tracking, we created a reaction-diffusion simulation to model mitochondrial network motion and remodeling events. MitoTNT uses spatial proximity and network topology to compute an optimal tracking assignment. Here we present MitoTNT, the first-in-class software for Mitochondrial Temporal Network Tracking in 4D live-cell fluorescence microscopy data. While lattice light-sheet microscopy has recently made it possible to image mitochondria in 4D, quantitative analysis methods for the resulting datasets have been lacking. Dysregulation of this four-dimensional (4D: x,y,z,time) network is implicated in numerous diseases ranging from cancer to neurodegeneration. Mitochondria form a network in the cell that rapidly changes through fission, fusion, and motility. Trump’s address in and of itself was a doozy - you can read Vox’s winners and losers wrap-up of it here. If you opted out of watching Trump’s speech on Tuesday, you probably missed the paper rip heard around the world - and everything else that happened in the hour-plus leading up to it.Īt the start of the evening when Trump entered the chamber, Pelosi offered her hand to the president as he gave her a copy of his speech, but he didn’t take it perhaps he didn’t see it or chose to ignore it. And in a moment of increasing polarization, everything is a proxy for what we believe. The emotions aren’t about paper or salad - they’re a stand-in for much more deep-seated, complicated disagreements in America. The reality of the civility debate, whether it’s Pelosi ripping up a speech or a restaurant refusing to serve Sarah Sanders a meal, is that it represents much more. And yet here we are the day after, and what’s getting the most airtime is whether Nancy ripping up Don’s papers was too mean or just mean enough. There are myriad fact-checks of Trump’s speech, and there’s plenty of coverage of the content of what he said, how it was received, and what it meant. q2GjCEJgwn- Seth Harris February 5, 2020 The #PelosiTantrum is a tragic image of how divided our country is. This is what building bridges to the American people looks like. Case in point: the hashtags trending on Twitter on Wednesday morning, including #PettyPelosi, #PelosiMeltdown, #NancyTheRipper, and #NancyPelosiROCKS. Yet again, we are debating what civility means - and whether it matters - in such a polarized, high-stakes era. (Trump fails to take the high road in most things, but sure.) On the right, it’s being scorned, and Pelosi is being criticized for not taking the “high road” in her actions. Pelosi’s act of defiance is being celebrated on the left as the rejection of a president who has just been impeached and filled his State of the Union address with hateful rhetoric and lies. The speaker of the House delivered yet another GIFable moment - and, with the flick of a wrist, reminded Americans that she, too, has a point to make, and needs a lot fewer words and braggadocio than the president to make it. Viewers noticed, and video of Pelosi tearing up Trump’s speech quickly went viral online. She went about her protest calmly, but she made her point. But it was Pelosi’s small gesture that cut deepest. Other Democrats had also protested Trump’s address, with many opting not to attend and some walking out mid-speech. ![]() ![]() Mandel Ngan/AFP via Getty ImagesĪfter Trump wrapped up his address on Tuesday, Pelosi, who alongside Vice President Mike Pence was seated behind the president during his speech, stood and tore in half the copy of his speech he had handed her at the outset of the evening. Nancy Pelosi begins to rip a copy of President Trump’s State of the Union address. ![]() This is useful for producing all-quad meshes for example. MeshLab is a tool oriented towards processing large meshes and provides a set of tools for editing, cleaning, and converting meshes. This is the 3d software/environment that will work best together with MakeHuman A set of female gowns and dresses by Elvaerwyn: dress02cc-by.zip (145 mb) Included assets Asset type Thumbnail Asset name Author Source License clothes elvscrochetbabydoll Elvaerwyn asset repo CC-BY clothes elvsdoublehandkerchiefhalterdress Elvaerwyn asset repo CC-BY clothes elvsfashionstylizedqipoa Elvaerwyn asset repo CC-BY clothes elvsfrilledpartydress Elvaerwyn asset repo CC. These tools are not part of MakeHuman, nor managed by MakeHuman, but are often used in the same pipeline.īlender is an open source 3d modeler, ray tracer and a whole lot else. For plain Debian see this instruction for how to enable PPA. Following the natural layered skin dynamics, the Realistic Human Skin library starts from the muscle layer (normal map), and then Skin Details, Blemish on-top, and Acquired Elements like tattoos, finally determine Body Hair on the outermost surface. Using MakeHuman 1.2.x you can download these assets from within the application.įor Debian/Ubuntu derivates (such as any modern version of Ubuntu, Mint and so on), see the makehuman-official PPA for 1.1.x. More assets for MakeHuman can be found in the online repository. These are bundled in the 1.2.x releases and in the nightly builds.Įxtra assets such as clothes, hair and skins Windows: 'Documents\makehuman\v1\data\skins' on Windows Vista/7/8/10' or MY DOCUMENTS\makehuman\v1\data\skins. FAQ:Where are my MakeHuman files found (where is my HOME directory). In total are 200 high quality skin, square framed and rounded framed. How do I install it Like other third party assets (e.g., clothes, body parts, or targets), skins are installed in the appropriate data-folder in the home directory. If you run from source, you will most likely also want some of the commonly used plugins, such as MHX2 and the asset downloader. These can be found on the plugins page. This pack can speed up your concept or work. If you are looking for MPFB2, you can find download links at the MPFB downloads page. ![]() If you want to download the source code for MakeHuman and/or run from a source snapshot, see the MakeHuman repository on Github. Look for the file named *-nightly-windows.zip. We are still producing nightly builds (see which version should I download?), which can be found in the download directory. By using this, you can download assets from within MakeHuman instead of doing so manually.At this point we recommended that you download the stable release (1.2.0) ![]() If you plan to download many clothes, it's probably more convenient to do so via the "community assets" plugin found in the community-plugins repository. Unlike other textures, we explicitly want to have the mip maps look different. Keep in mind that the actual value depends on scale/distance, age, and wet/dryness of the skin that you are trying to simulate. If an asset is broken or if you want to nominate an asset for "community favorite", you can use the tag request system to request that a moderator tag the item. For skin, it is best to start with a constant Roughness value of around 0.4 and tweak from there. If you rather browse by thumbnail, there is also a thumbnail gallery.Ĭlick here if you want to upload new clothes. If you do not have a forum account, go here and click "register". You can log in using your forum username and password. In order to comment contributions or upload new items you need to be logged in. A set of high-res eyebrows by Mindfront: eyebrows01cc0.zip (10 mb) Included assets Asset type Thumbnail Asset name Author Source License clothes mindfronteyebrows01 Mindfront asset repo CC0 clothes mindfronteyebrows02 Mindfront asset repo CC0 clothes mindfronteyebrows03 Mindfront asset repo CC0 clothes mindfronteyebrows. In this pack you will find Dream SMP member skins, including lore and special skins In this pack you will find Dream SMP member skins, including lore related skins Check the skins bellow: This is the pack. New users may be interested in the MakeClothes tutorial by VscorpianC. If you wish more information on clothes (including on how to create them), take a look in the wiki (particularly the FAQ on how to install clothes). Note that they are not created, nor endorsed, by the MakeHuman crew. These are user contributed clothes for MakeHuman. |
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